Depin 10mg 30 Capsules

Babies: Not applicable. Lactating mothers: This tablet is considered safe to use during breastfeeding.
Limited human data states that the drug does not represent any severe risks to the baby. Pregnancy: This tablet is considered unsafe to use during pregnancy. Animal studies state that drug has shown harmful effects on the developing baby.
However, there are limited studies on humans. Please consult your doctor. Driving: Caution is advised while driving as it may cause dizziness or weakness due to low blood pressure.
Do not drive if these symptoms occur. Alcohol: Caution is advised while consuming alcohol along with this tablet. Please consult your doctor. Kidney: This tablet is considered safe to use in patients with kidney disease.
Dose adjustment of this medication is not required in patients. Please consult your doctor. Liver: This tablet should be used with caution with patients with liver disease.
Dose adjustment of this medication is required in patients. Please consult your doctor..

Dizziness Edema (swelling) Fatigue Flushing (sense of warmth in the face, ears, neck and trunk) Headache Palpitations Constipation.

Depin is a calcium channel blocker that works by inhibiting the influx of extracellular calcium ions across the myocardial and vascular smooth muscle cell membranes. These inhibit calcium and vascular smooth muscle contraction, which occurs during depolarization, reducing the peripheral arterial vascular resistance and dilating coronary arteries.
These actions reduce blood pressure and increase the supply of oxygen to the heart, relieving angina..

If you miss a dose, take it as soon as possible. If it is near the time of the next dose, then skip the missed dose.
Take the prescribed dose on your regular time daily. Don't double the dose to catch up with the missed dose..

• To ensure better efficacy continue to take medicine at a fixed time • A sudden drop in your blood pressure may be noticed, especially when taking it for the first time. To lower the chance of feeling dizzy or passing out, get up slowly if you have been sitting or lying down • It can cause ankle or foot swelling.
To reduce the swelling, raise your legs while you are sitting down. Consult your doctor if these do not subside • It may cause dizziness.
Do not drive or perform any activity that requires mental focus until you know how this medication affects you • Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding. • Go for regular exercise, maintain a balanced weight • Include a good hygienic diet • Avoid smoking and alcohol consumption.

Contraindicated • Depin + Everolimus: Depin will decrease the level or effect of everolimus by p-glycoprotein (mdr1) efflux transporter • Depin + Pimozide: Depin increases levels of pimozide by decreasing metabolism. Risk of qt interval prolongation Serious • Depin + Erythromycin: Depin will increase the level or effect of erythromycin by affecting hepatic/intestinal enzyme cyp3a4 metabolism • Depin + Amlodipine: Depin will increase the level or effect of amlodipine by affecting hepatic/intestinal enzyme cyp3a4 metabolism Monitor closely • Depin + Ketoconazole: Ketoconazole increases levels of depin by decreasing metabolism.